Comparative modeling of the three-dimensional structures of family 3 glycoside hydrolases.

Comparative modeling of the three-dimensional structures of family 3 glycoside hydrolases.

Posted on by Mathew

There are roughly 100 identified members of the family 3 group of glycoside hydrolases, most of that are categorized as beta-glucosidases and originate from microorganisms. The solely family 3 glycoside hydrolase for which a three-dimensional construction is accessible is a beta-glucan exohydrolase from barley. The structural coordinates of the barley enzyme is used right here to mannequin representatives from distinct phylogenetic clusters inside the family.

The majority of family 3 hydrolases have an NH(2)-terminal (alpha/beta)(8) barrel linked by a brief linker to a second area, which adopts an (alpha/beta)(6) sandwich fold. In two bacterial beta-glucosidases, the order of the domains is reversed. The catalytic nucleophile, equal to D285 of the barley beta-glucan exohydrolase, is totally conserved throughout the family.

It is situated on area 1, in a shallow web site pocket close to the interface of the domains. The doubtless catalytic acid in the barley enzyme, E491, is on area 2. Although equally positioned acidic residues are current in carefully associated members of the family, the equal amino acid in additional distantly associated members is both too removed from the energetic web site or absent. In the latter instances, the function of catalytic acid might be assumed by different acidic amino acids from area 1.

The crystal construction of P. carrageenovora kappa-carrageenase is the first three-dimensional construction of a carrageenase. Its tunnel-shaped energetic web site, the first to be reported for enzymes apart from cellulases, means that such tunnels are related to the degradation of stable polysaccharides. Clan-B glycoside hydrolases fall into two subgroups, one with catalytic equipment held by an ancestral beta bulge, and the different during which it’s held by a daily beta strand.

At subsite -1, all of these hydrolases exhibit an fragrant amino acid that interacts with the hexopyranose ring of the monosaccharide present process catalysis. In addition, in kappa-carrageenases, an arginine residue acknowledges the sulfate-ester substituents of the beta-linked kappa-carrageenan monomers. It additionally seems that, along with the nucleophile and acid/base catalysts, two different amino acids are concerned with the catalytic cycle, accelerating the deglycosylation step.

Comparative modeling of the three-dimensional structures of family 3 glycoside hydrolases.

Physiological function of the alpha1- and alpha2-isoforms of the Na+-Okay+-ATPase and organic significance of their cardiac glycoside binding web site.

An attention-grabbing characteristic of Na+-Okay+-ATPase is that it comprises 4 isoforms of the catalytic alpha-subunit, every with a tissue-specific distribution. Our laboratory has used gene focusing on to outline the practical function of the alpha1- and alpha2-isoforms.

While knockout mice demonstrated the significance of the alpha1- and alpha2-isoforms for survival, the knockin mice, during which every isoform may be individually inhibited by ouabain and its perform decided, demonstrated that each isoforms are regulators of cardiac muscle contractility. Another intriguing side of the Na+-Okay+-ATPase is that it comprises a binding web site for cardiac glycosides, reminiscent of digoxin.

Conservation of this web site means that it might have an in vivo function and {that a} pure ligand should exist to work together with this web site. In reality, cardiac glycoside-like compounds have been noticed in mammals. Our current research demonstrates that the cardiac glycoside binding web site of the Na+-Okay+-ATPase performs a job in the regulation of blood stress and that it mediates each ouabain-induced and ACTH-induced hypertension in mice. Whereas power administration of ouabain or ACTH brought about hypertension in wild-type mice, it had no impact on blood stress in mice with a ouabain-resistant alpha2-isoform of Na+-Okay+-ATPase.

Interestingly, animals with the ouabain-sensitive alpha1-isoform and a ouabain-resistant alpha2-isoform develop ACTH-induced hypertension to a larger extent than wild-type animals. Taken collectively, these outcomes show that the cardiac glycoside binding of the Na+-Okay+-ATPase has a physiological function and suggests a perform for a naturally occurring ligand that’s stimulated by administration of ACTH.

Structural evaluation of dispersin B, a biofilm-releasing glycoside hydrolase from the periodontopathogen Actinobacillus actinomycetemcomitans.

Bacteria in a biofilm are enmeshed in a self-synthesized extracellular polysaccharide matrix that holds the micro organism collectively in a mass and firmly attaches the bacterial mass to the underlying floor. A serious element of the extracellular polysaccharide matrix in a number of phylogenetically various micro organism is PGA, a linear polymer of N-acetylglucosamine residues in beta(1,6)-linkage.

PGA is produced by the Gram-negative periodontopathogen Actinobacillus actinomycetemcomitans in addition to by the Gram-positive device-associated pathogen Staphylococcus epidermidis. We just lately reported that A.actinomycetemcomitans produces a soluble glycoside hydrolase named dispersin B, which degrades PGA.

Here, we current the crystal construction of dispersin B at 2.0A in complicated with a glycerol and an acetate ion at the energetic web site. The enzyme crystallizes in the orthorhombic area group C222(1) with cell dimensions a=41.02A, b=86.13A, c=185.77A. The core of the enzyme consists a (beta/alpha)(8) barrel topology just like different beta-hexosaminidases however important variations exist in the association of loops hovering in the neighborhood of the energetic web site.

The location and interactions of the glycerol and acetate moieties along side the sequence evaluation recommend that dispersin B cleaves beta(1,6)-linked N-acetylglucosamine polymer utilizing a catalytic equipment just like different family 20 hexosaminidases which cleave beta(1,4)-linked N-acetylglucosamine residues. Mechanistically, p53 discount occurred not at the mRNA ranges however at the protein ranges, in consequence of diminished protein synthesis reasonably than enhanced degradation.

Alpha 1 Acid Glycoprotein (A1-AGP), Rabbit
A1AG23-N-25 25 ug
EUR 286

Alpha 1 Acid Glycoprotein (A1-AGP), Turkey
A1AG24-N-100 100 ug
EUR 164

Alpha-1-Acid Glycoprotein Protein, Mouse, control for western
A1AG18-C 100 ul
EUR 286

Human Alpha-1-Acid Glycoprotein 2 (ORM2, AGP2) AssayMax ELISA Kit
EG2713-1 96 Well Plate
EUR 417

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Mu-10x96wellstestplate 10x96-wells test plate
EUR 4391.16
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Mu-1x48wellstestplate 1x48-wells test plate
EUR 449.27
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Mu-1x96wellstestplate 1x96-wells test plate
EUR 598.96
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Mu-5x96wellstestplate 5x96-wells test plate
EUR 2395.32
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
4-SEA816Mu
  • EUR 4442.00
  • EUR 2346.00
  • EUR 599.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Alpha-1-Acid Glycoprotein ELISA Kit (a1AGP)
RK02553 96 Tests
EUR 521

Mouse Alpha-1-Acid Glycoprotein(a1AGP)ELISA kit
GA-E0763MS-48T 48T
EUR 336

Mouse Alpha-1-Acid Glycoprotein(a1AGP)ELISA kit
GA-E0763MS-96T 96T
EUR 534

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-Mu-48Tests 48 Tests
EUR 489

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-Mu-96Tests 96 Tests
EUR 677

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-Mu-48Tests 48 Tests
EUR 511

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-Mu-96Tests 96 Tests
EUR 709

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-Mu-48T 48T
EUR 489
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-Mu-96T 96T
EUR 635
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Orm1/ Alpha-1-acid glycoprotein 1 ELISA Kit
E1663Mo 1 Kit
EUR 563

Mouse Alpha-1-Acid Glycoprotein 1 (ORM1) ELISA Kit
abx575963-96tests 96 tests
EUR 668

Mouse Alpha-1-Acid Glycoprotein 1 (ORM1) ELISA Kit
abx254506-96tests 96 tests
EUR 668

Mouse Alpha-1-Acid Glycoprotein 1 (ORM1) ELISA Kit
20-abx153574
  • EUR 6642.00
  • EUR 3542.00
  • EUR 825.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Alpha- 1- acid glycoprotein 1, Orm1 ELISA KIT
ELI-02756m 96 Tests
EUR 865

Mouse Alpha 1 acid glycoprotein 1(ORM1) ELISA kit
E03A1939-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Alpha 1 acid glycoprotein 1(ORM1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Alpha 1 acid glycoprotein 1(ORM1) ELISA kit
E03A1939-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Alpha 1 acid glycoprotein 1(ORM1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Alpha 1 acid glycoprotein 1(ORM1) ELISA kit
E03A1939-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Alpha 1 acid glycoprotein 1(ORM1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Alpha 1 Acid Glycoprotein (A1-AGP), Human Plasma
A1AG15-N 1 mg
EUR 164

Alpha 1 Acid Glycoprotein protein (Mouse)
30-1035 25 ug
EUR 298
Description: Purified native Mouse Alpha 1 Acid Glycoprotein protein

Human Alpha 1 Acid Glycoprotein ELISA Kit
PRB-5044 96 assays
EUR 572
Description: Our Human ?1AG ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of human ?1AG in plasma, serum, urine, cell or tissue lysate samples. The kit has a detection sensitivity limit of 30 pg/mL human ?1AG. Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples.

Mouse Alpha-1-acid glycoprotein 2(ORM2) ELISA kit
CSB-EL017238MO-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse Alpha-1-acid glycoprotein 2 (ORM2) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Alpha-1-acid glycoprotein 2(ORM2) ELISA kit
1-CSB-EL017238MO
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Alpha-1-acid glycoprotein 2(ORM2) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ELISA kit for Mouse a1AGP (Alpha-1-Acid Glycoprotein)
ELK1621 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Alpha-1-Acid Glycoprotein from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Mouse Alpha- 1- acid glycoprotein 3, Orm3 ELISA KIT
ELI-24710m 96 Tests
EUR 865

Mouse Alpha- 1- acid glycoprotein 2, AGP2 ELISA Kit
ELI-05766m 96 Tests
EUR 865

Alpha-1-Acid Glycoprotein Protein, Dog, control for western
A1AG17-C 100 ul
EUR 286

Alpha 1 Acid Glycoprotein (A1-AGP), Pig/Porcine/Swine
A1AG22-N-100 100 ug
EUR 164

ELISA kit for Mouse AGP1 (Alpha-1-Acid Glycoprotein 1)
E-EL-M1250 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Mouse AGP1 (Alpha-1-Acid Glycoprotein 1) in samples from Serum, Plasma, Cell supernatant

Human alpha 1 Acid Glycoprotein
abx060927-1mg 1 mg
EUR 370

Alpha-1 acid glycoprotein Antibody
48525-100ul 100ul
EUR 333

Alpha-1 acid glycoprotein Antibody
48525-50ul 50ul
EUR 239

alpha 1 Acid Glycoprotein antibody
20C-CR6001G 1 ml
EUR 151
Description: Goat polyclonal alpha 1 Acid Glycoprotein

Alpha 1 Acid Glycoprotein protein
30-1034 1 mg
EUR 263
Description: Purified native Human Alpha 1 Acid Glycoprotein protein

alpha 1 Acid Glycoprotein protein
30-AA01 1 mg
EUR 148
Description: Purified native Human alpha 1 Acid Glycoprotein protein

alpha 1 Acid Glycoprotein protein
30R-AA003 10 mg
EUR 392
Description: Purified native Human alpha 1 Acid Glycoprotein protein

anti-Alpha 1 Acid Glycoprotein
YF-PA13551 50 ug
EUR 363
Description: Mouse polyclonal to Alpha 1 Acid Glycoprotein

anti-Alpha 1 Acid Glycoprotein
YF-PA13552 100 ug
EUR 403
Description: Rabbit polyclonal to Alpha 1 Acid Glycoprotein

Alpha 1 Acid Glycoprotein Antibody
7010-100
EUR 338

Alpha 1 Acid Glycoprotein Antibody
7010-30T
EUR 146

Cattle Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Bo-10x96wellstestplate 10x96-wells test plate
EUR 5098.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, urine and other biological fluids.

Cattle Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Bo-1x48wellstestplate 1x48-wells test plate
EUR 507.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, urine and other biological fluids.

Cattle Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Bo-1x96wellstestplate 1x96-wells test plate
EUR 682.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, urine and other biological fluids.

Cattle Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Bo-5x96wellstestplate 5x96-wells test plate
EUR 2769.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, urine and other biological fluids.

Cattle Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
4-SEA816Bo
  • EUR 5149.00
  • EUR 2720.00
  • EUR 683.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Cattle Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, urine and other biological fluids with no significant corss-reactivity with analogues from other species.

LISA for Alpha-1-Acid Glycoprotein)ELISA kit
SEA816Ga-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of LISA for Alpha-1-Acid Glycoprotein) in serum, plasma and other biological fluids.

LISA for Alpha-1-Acid Glycoprotein)ELISA kit
SEA816Ga-1x48wellstestplate 1x48-wells test plate
EUR 468.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of LISA for Alpha-1-Acid Glycoprotein) in serum, plasma and other biological fluids.

LISA for Alpha-1-Acid Glycoprotein)ELISA kit
SEA816Ga-1x96wellstestplate 1x96-wells test plate
EUR 626.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of LISA for Alpha-1-Acid Glycoprotein) in serum, plasma and other biological fluids.

LISA for Alpha-1-Acid Glycoprotein)ELISA kit
SEA816Ga-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of LISA for Alpha-1-Acid Glycoprotein) in serum, plasma and other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Hu-10x96wellstestplate 10x96-wells test plate
EUR 3409.41
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Hu-1x48wellstestplate 1x48-wells test plate
EUR 368.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Hu-1x96wellstestplate 1x96-wells test plate
EUR 483.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Hu-5x96wellstestplate 5x96-wells test plate
EUR 1875.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
4-SEA816Hu
  • EUR 3460.00
  • EUR 1826.00
  • EUR 484.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Pig Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Po-10x96wellstestplate 10x96-wells test plate
EUR 5098.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma and other biological fluids.

Pig Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Po-1x48wellstestplate 1x48-wells test plate
EUR 507.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma and other biological fluids.

Pig Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Po-1x96wellstestplate 1x96-wells test plate
EUR 682.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma and other biological fluids.

Pig Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Po-5x96wellstestplate 5x96-wells test plate
EUR 2769.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma and other biological fluids.

Pig Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
4-SEA816Po
  • EUR 5149.00
  • EUR 2720.00
  • EUR 683.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Pig Alpha-1-Acid Glycoprotein (a1AGP) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rat Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Ra-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Ra-1x48wellstestplate 1x48-wells test plate
EUR 468.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Ra-1x96wellstestplate 1x96-wells test plate
EUR 626.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
SEA816Ra-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Alpha-1-Acid Glycoprotein (a1AGP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
4-SEA816Ra
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Chicken alpha 1-acid glycoprotein (OGCHI) ELISA kit
CSB-EL017237CH-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Chicken alpha 1-acid glycoprotein (OGCHI) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Chicken alpha 1-acid glycoprotein (OGCHI) ELISA kit
1-CSB-EL017237CH
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Chicken alpha 1-acid glycoprotein (OGCHI) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Alpha-1-Acid Glycoprotein ELISA Kit (a1AGP)
RK03451 96 Tests
EUR 521

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-b-48Tests 48 Tests
EUR 555

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-b-96Tests 96 Tests
EUR 771

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-Hu-48Tests 48 Tests
EUR 478

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-Hu-96Tests 96 Tests
EUR 662

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-p-48Tests 48 Tests
EUR 555

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RD-a1AGP-p-96Tests 96 Tests
EUR 771

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-b-48Tests 48 Tests
EUR 580

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-b-96Tests 96 Tests
EUR 807

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-Hu-48Tests 48 Tests
EUR 500

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-Hu-96Tests 96 Tests
EUR 692

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-p-48Tests 48 Tests
EUR 580

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
RDR-a1AGP-p-96Tests 96 Tests
EUR 807

Bovine ORM1/ Alpha-1-acid glycoprotein ELISA Kit
E0196Bo 1 Kit
EUR 717

Rat Orm1/ Alpha-1-acid glycoprotein ELISA Kit
E0716Ra 1 Kit
EUR 563

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-p-96T 96T
EUR 715
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma or other biological fluids.

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-b-48T 48T
EUR 547
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, urine or other biological fluids.

Bovine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-b-96T 96T
EUR 715
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, urine or other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-Hu-48T 48T
EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-Hu-96T 96T
EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Porcine Alpha-1-Acid Glycoprotein (a1AGP) ELISA Kit
DLR-a1AGP-p-48T 48T
EUR 547
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Alpha-1-Acid Glycoprotein (a1AGP) in samples from serum, plasma or other biological fluids.

Bovine Alpha-1-Acid Glycoprotein ELISA Kit (a1AGP)
RK00434 96 Tests
EUR 521

Alpha 1-Acid GlycoProtein ELISA Kit (Chicken) (OKIA00015)
OKIA00015 96 Wells
EUR 596
Description: Description of target: Functions as transport protein in the blood stream.;Species reactivity: Chicken;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.975 ng/ml

Alpha 1-Acid GlycoProtein ELISA Kit (Dog) (OKIA00020)
OKIA00020 96 Wells
EUR 675
Description: Description of target: Functions as transport protein in the blood stream.;Species reactivity: Dog;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.706 ng/ml

Alpha 1-Acid GlycoProtein ELISA Kit (Human) (OKIA00047)
OKIA00047 96 Wells
EUR 544
Description: Description of target: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.089 ng/ml

Alpha-1 Acid GlycoProtein ELISA Kit (Rat) (OKIA00132)
OKIA00132 96 Wells
EUR 596
Description: Description of target: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Appears to function in modulating the activity of the immune system during the acute-phase reaction.;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.245 ng/ml

ELISA kit for Rat Alpha-1-acid glycoprotein
EK2282 96 tests
EUR 536
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Alpha-1-acid glycoprotein in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Alpha-1-acid glycoprotein
EK2284 96 tests
EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Alpha-1-acid glycoprotein in samples from serum, plasma, tissue homogenates and other biological fluids.

Chicken a1AGP(Alpha-1-Acid Glycoprotein) ELISA Kit
ECH0091 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Chicken;Sensitivity: 3.75 ng/ml

Porcine Alpha- 1- acid glycoprotein, ORM1 ELISA KIT
ELA-E0816p 96 Tests
EUR 928

Rat Alpha- 1- acid glycoprotein, Orm1 ELISA KIT
ELI-02754r 96 Tests
EUR 886

Bovine Alpha- 1- acid glycoprotein, ORM1 ELISA KIT
ELI-02755b 96 Tests
EUR 928

Rabbit Alpha- 1- acid glycoprotein, ORM1 ELISA KIT
ELI-02758Ra 96 Tests
EUR 928

Mouse Alpha-1-Acid Glycoprotein (a1AGP) Protein
20-abx065226
  • EUR 551.00
  • EUR 244.00
  • EUR 1595.00
  • EUR 648.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant mouse Alpha-1-acid glycoprotein 2
P1666 100ug Ask for price
Description: Recombinant protein for mouse Alpha-1-acid glycoprotein 2

Human Alpha-1-acid glycoprotein 1(ORM1) ELISA kit
CSB-EL017237HU-24T 1 plate of 24 wells
EUR 165
Description: Quantitativecompetitive ELISA kit for measuring Human Alpha-1-acid glycoprotein 1 (ORM1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Alpha-1-acid glycoprotein 1(ORM1) ELISA kit
1-CSB-EL017237HU
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativecompetitive ELISA kit for measuring Human Alpha-1-acid glycoprotein 1(ORM1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

The mobile sensitivity to drug-induced p53 discount was not related to the ranges of alphasubunits of Na(+)/Okay(+)-ATPase in numerous cell traces. Although decreasing extracellular Okay(+) didn’t cut back p53 as did ouabain and digoxin, it did potentiate each digoxin- and ouabain-induced p53 discount in delicate traces.

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