Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: structure and function of a large, enigmatic family.

Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: structure and function of a large, enigmatic family.

Posted on by Mathew

Currently, the comparatively excessive price of enzymes resembling glycoside hydrolases that catalyze cellulose hydrolysis represents a barrier to commercialization of a biorefinery succesful of producing renewable transportable fuels resembling ethanol from ample lignocellulosic biomass. Among the numerous households of glycoside hydrolases that catalyze cellulose and hemicellulose hydrolysis, few are extra enigmatic than family 61 (GH61), initially categorized primarily based on measurement of very weak endo-1,4-beta-d-glucanase exercise in a single family member.

Here we present that sure GH61 proteins lack measurable hydrolytic exercise by themselves however within the presence of varied divalent metallic ions can considerably scale back the overall protein loading required to hydrolyze lignocellulosic biomass. We additionally solved the structure of one extremely lively GH61 protein and discover that it’s devoid of conserved, carefully juxtaposed acidic aspect chains that would function normal proton donor and nucleophile/base in a canonical hydrolytic response, and we conclude that the GH61 proteins are unlikely to be glycoside hydrolases.

Structure-based mutagenesis exhibits the significance of a number of conserved residues for GH61 function. By incorporating the gene for one GH61 protein into a industrial Trichoderma reesei pressure producing excessive ranges of cellulolytic enzymes, we’re in a position to scale back by 2-fold the overall protein loading (and therefore the associated fee) required to hydrolyze lignocellulosic biomass. Several members of the glycoside hydrolase 61 (GH61) family of proteins have lately been proven to dramatically improve the breakdown of lignocellulosic biomass by microbial hydrolytic cellulases.

However, purified GH61 proteins have neither demonstrable direct hydrolase exercise on varied polysaccharide or lignacious parts of biomass nor an obvious hydrolase lively web site. Cellobiose dehydrogenase (CDH) is a secreted flavocytochrome produced by many cellulose-degrading fungi with no well-understood organic function. Here we exhibit that the binary mixture of Thermoascus aurantiacus GH61A (TaGH61A) and Humicola insolens CDH (HiCDH) cleaves cellulose into soluble, oxidized oligosaccharides.

Cardiac glycosides as novel most cancers therapeutic brokers.

The class of steroid-like compounds designated cardiac glycosides contains well-known medicine resembling digoxin, digitoxin, and ouabain. Their continued efficacy in therapy of congestive coronary heart failure and as anti-arrhythmic brokers is properly appreciated. Less well-known, nonetheless, is the rising function of this class of compounds within the prevention and/or therapy of proliferative illnesses resembling most cancers.

New findings throughout the previous 5 years have revealed these compounds to be concerned in complicated cell-signal transduction mechanisms, leading to selective management of human tumor however not regular mobile proliferation. As such, they characterize a promising kind of focused most cancers chemotherapy. New scientific research of their anticancer potential as single or adjuvant therapies might present perception into these probably useful therapeutic choices.

Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: structure and function of a large, enigmatic family.

This evaluate focuses on latest findings on mobile pharmacology of cardiac glycosides as they relate to therapy of human most cancers and makes an attempt to elucidate why these brokers have been missed previously. TaGH61A-HiCDH exercise on cellulose is proven to be nonredundant with the actions of canonical endocellulase and exocellulase enzymes in microcrystalline cellulose cleavage, and whereas the mixture of TaGH61A and HiCDH cleaves extremely crystalline bacterial cellulose, it doesn’t cleave soluble cellodextrins.

GH61 and CDH proteins are coexpressed and secreted by the thermophilic ascomycete Thielavia terrestris in response to environmental cellulose, and the mixed actions of T. terrestris GH61 and T. terrestris CDH are proven to synergize with T. terrestris cellulose hydrolases within the breakdown of cellulose. The motion of GH61 and CDH on cellulose might represent an essential, however missed, organic oxidoreductive system that features in microbial lignocellulose degradation and has purposes in industrial biomass utilization.

Cardiac glycosides exert anticancer results by inducing immunogenic cell demise.

Some profitable chemotherapeutics, notably anthracyclines and oxaliplatin, induce a kind of cell stress and demise that’s immunogenic, therefore changing the affected person’s dying most cancers cells into a vaccine that stimulates antitumor immune responses.

By means of a fluorescence microscopy platform that permits for the automated detection of the biochemical hallmarks of such a peculiar cell demise modality, we recognized cardiac glycosides (CGs) as exceptionally environment friendly inducers of immunogenic cell demise, an impact that was related to the inhibition of the plasma membrane Na(+)- and Okay(+)-dependent adenosine triphosphatase (Na(+)/Okay(+)-ATPase). CGs exacerbated the antineoplastic results of DNA-damaging brokers in immunocompetent however not immunodeficient mice.

Moreover, most cancers cells succumbing to a mixture of chemotherapy plus CGs may vaccinate syngeneic mice in opposition to a subsequent problem with residing cells of the identical kind. Finally, retrospective scientific analyses revealed that the administration of the CG digoxin throughout chemotherapy had a optimistic affect on total survival in cohorts of breast, colorectal, head and neck, and hepatocellular carcinoma sufferers, particularly once they had been handled with brokers apart from anthracyclines and oxaliplatin.

Metagenomic and bioinformatic approaches had been used to characterize plant biomass conversion throughout the foregut microbiome of Australia’s “mannequin” marsupial, the Tammar wallaby (Macropus eugenii). Like the termite hindgut and bovine rumen, key enzymes and modular buildings attribute of the “free enzyme” and “cellulosome” paradigms of cellulose solubilization stay both poorly represented or elusive to seize by shotgun sequencing strategies.

Instead, multigene polysaccharide utilization loci-like programs coupled with genes encoding beta-1,4-endoglucanases and beta-1,4-endoxylanases–which haven’t been beforehand encountered in metagenomic datasets–were recognized, as had been a numerous set of glycoside hydrolases focusing on noncellulosic polysaccharides.

ELISA kit for Rat DNA-3-methyladenine glycosylase (MPG)
KTE100595-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-3-methyladenine glycosylase (MPG)
KTE100595-96T 96T
EUR 539
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Mpg ELISA Kit| Rat DNA-3-methyladenine glycosylase ELISA Kit
EF019079 96 Tests
EUR 689

ELISA kit for Mouse DNA-3-methyladenine glycosylase (MPG)
KTE70981-48T 48T
EUR 332
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-3-methyladenine glycosylase (MPG)
KTE70981-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-3-methyladenine glycosylase (MPG)
KTE70981-96T 96T
EUR 539
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human DNA-3-methyladenine glycosylase (MPG)
KTE61567-48T 48T
EUR 332
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Human DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human DNA-3-methyladenine glycosylase (MPG)
KTE61567-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Human DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human DNA-3-methyladenine glycosylase (MPG)
KTE61567-96T 96T
EUR 539
  • MPG (N-Methylpurine DNA Glycosylase) is a Protein Coding gene. Among its related pathways are Recognition and association of DNA glycosylase with site containing an affected purine and Telomere C-strand (Lagging Strand) Synthesis. GO annotations rela
  • Show more
Description: Quantitative sandwich ELISA for measuring Human DNA-3-methyladenine glycosylase (MPG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Mpg ELISA Kit| Mouse DNA-3-methyladenine glycosylase ELISA Kit
EF015702 96 Tests
EUR 689

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
DLR-MPG-Hu-48T 48T
EUR 517
  • Should the Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Methylpurine DNA Glycosylase (MPG) in samples from tissue homogenates or other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
DLR-MPG-Hu-96T 96T
EUR 673
  • Should the Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Methylpurine DNA Glycosylase (MPG) in samples from tissue homogenates or other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
RDR-MPG-Hu-48Tests 48 Tests
EUR 544

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
RDR-MPG-Hu-96Tests 96 Tests
EUR 756

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
RD-MPG-Hu-48Tests 48 Tests
EUR 521

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
RD-MPG-Hu-96Tests 96 Tests
EUR 723

Rat N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
abx391719-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Rat N-Methylpurine DNA Glycosylase (MPG) Protein
20-abx068316
  • EUR 732.00
  • EUR 286.00
  • EUR 2263.00
  • EUR 871.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx008970
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx004144
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx210392
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx210408
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx103054
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx103055
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx103056
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx114134
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
abx146076-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
20-abx173843
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

N-Methylpurine DNA Glycosylase (MPG) Antibody
abx235281-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

N-Methylpurine DNA Glycosylase (MPG) Antibody
abx432982-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Recombinant N-Methylpurine DNA Glycosylase (MPG)
4-RPH625Hu01
  • EUR 478.11
  • EUR 231.00
  • EUR 1517.92
  • EUR 572.64
  • EUR 1045.28
  • EUR 383.00
  • EUR 3644.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P29372
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 34.8kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human N-Methylpurine DNA Glycosylase expressed in: E.coli

Recombinant N-Methylpurine DNA Glycosylase (MPG)
4-RPH625Mu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q04841
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 31.4kDa
  • Isoelectric Point: 8.9
Description: Recombinant Mouse N-Methylpurine DNA Glycosylase expressed in: E.coli

Recombinant N-Methylpurine DNA Glycosylase (MPG)
4-RPH625Ra01
  • EUR 521.12
  • EUR 242.00
  • EUR 1679.20
  • EUR 626.40
  • EUR 1152.80
  • EUR 412.00
  • EUR 4048.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P23571
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 33.5kDa
  • Isoelectric Point: 9.4
Description: Recombinant Rat N-Methylpurine DNA Glycosylase expressed in: E.coli

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
20-abx152371
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
abx390063-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
SEH625Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human N-Methylpurine DNA Glycosylase (MPG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human N-Methylpurine DNA Glycosylase (MPG) in tissue homogenates, cell lysates and other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
SEH625Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human N-Methylpurine DNA Glycosylase (MPG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human N-Methylpurine DNA Glycosylase (MPG) in tissue homogenates, cell lysates and other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
SEH625Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human N-Methylpurine DNA Glycosylase (MPG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human N-Methylpurine DNA Glycosylase (MPG) in tissue homogenates, cell lysates and other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
SEH625Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human N-Methylpurine DNA Glycosylase (MPG) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay:
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human N-Methylpurine DNA Glycosylase (MPG) in tissue homogenates, cell lysates and other biological fluids.

Human N-Methylpurine DNA Glycosylase (MPG) ELISA Kit
4-SEH625Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as N-Methylpurine DNA Glycosylase elisa. Alternative names of the recognized antigen: AAG
  • APNG
  • ADPG
  • CRA36.1
  • MDG
  • Mid1
  • PIG11
  • PIG16
  • Anpg
  • DNA-3-Methyladenine Glycosylase
  • Alkyladenine DNA Glycosylase
  • 3-alkyladenine DNA glycosylase
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human N-Methylpurine DNA Glycosylase (MPG) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human N-Methylpurine DNA Glycosylase ELISA Kit (MPG)
RK01873 96 Tests
EUR 521

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat)
4-PAH625Ra01
  • EUR 259.00
  • EUR 2708.00
  • EUR 670.00
  • EUR 328.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG)

Human N-Methylpurine DNA Glycosylase (MPG) Protein
20-abx068314
  • EUR 676.00
  • EUR 272.00
  • EUR 2054.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse N-Methylpurine DNA Glycosylase (MPG) Protein
20-abx068315
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human N-Methylpurine DNA Glycosylase (MPG) CLIA Kit
20-abx495496
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

ELISA kit for Human MPG (N-Methylpurine DNA Glycosylase)
ELK3239 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to N-Methylpurine DNA Glycosylase (MPG). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific
  • Show more
Description: A sandwich ELISA kit for detection of N-Methylpurine DNA Glycosylase from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-100ug
QP9282-ye-100ug 100ug
EUR 480

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-10ug
QP9282-ye-10ug 10ug
EUR 236

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-1mg
QP9282-ye-1mg 1mg
EUR 1885

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-200ug
QP9282-ye-200ug 200ug
EUR 744

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-500ug
QP9282-ye-500ug 500ug
EUR 1206

Recombinant Human DNA-3-methyladenine glycosylase Protein, His, Yeast-50ug
QP9282-ye-50ug 50ug
EUR 299

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), APC
4-PAH625Ra01-APC
  • EUR 364.00
  • EUR 3545.00
  • EUR 980.00
  • EUR 467.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), Biotinylated
4-PAH625Ra01-Biotin
  • EUR 325.00
  • EUR 2658.00
  • EUR 777.00
  • EUR 400.00
  • EUR 225.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Biotin.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), Cy3
4-PAH625Ra01-Cy3
  • EUR 444.00
  • EUR 4685.00
  • EUR 1265.00
  • EUR 581.00
  • EUR 261.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Cy3.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), FITC
4-PAH625Ra01-FITC
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with FITC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), HRP
4-PAH625Ra01-HRP
  • EUR 332.00
  • EUR 3089.00
  • EUR 866.00
  • EUR 421.00
  • EUR 213.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with HRP.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), PE
4-PAH625Ra01-PE
  • EUR 311.00
  • EUR 2856.00
  • EUR 804.00
  • EUR 393.00
  • EUR 202.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with PE.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human)
4-PAH625Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG)

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse)
4-PAH625Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG)

MPG N-Methylpurine-DNA Glycosylase Human Recombinant Protein
PROTP29372 Regular: 10ug
EUR 317
Description: MPG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 306 amino acids (1-298 a.a.) and having a molecular mass of 33.9kDa (Molecular weight on SDS-PAGE will appear higher).;MPG is fused to an 8 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Rat), APC-Cy7
4-PAH625Ra01-APC-Cy7
  • EUR 608.00
  • EUR 6970.00
  • EUR 1840.00
  • EUR 814.00
  • EUR 335.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Gln32~Met300)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC-Cy7.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), APC
4-PAH625Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), Biotinylated
4-PAH625Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Biotin.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), Cy3
4-PAH625Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Cy3.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), FITC
4-PAH625Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with FITC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), HRP
4-PAH625Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with HRP.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), PE
4-PAH625Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with PE.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), APC
4-PAH625Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), Biotinylated
4-PAH625Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Biotin.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), Cy3
4-PAH625Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with Cy3.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), FITC
4-PAH625Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with FITC.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), HRP
4-PAH625Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with HRP.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), PE
4-PAH625Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with PE.

Rat Uracil DNA Glycosylase ELISA kit
E02U0076-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Rat Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Uracil DNA Glycosylase ELISA kit
E02U0076-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Rat Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Uracil DNA Glycosylase ELISA kit
E02U0076-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Rat Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Human), APC-Cy7
4-PAH625Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Pro70~Thr296) with a peptide LCQALA
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC-Cy7.

N-Methylpurine DNA Glycosylase (MPG) Polyclonal Antibody (Mouse), APC-Cy7
4-PAH625Mu01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: MPG (Leu46~Gln315)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse N-Methylpurine DNA Glycosylase (MPG). This antibody is labeled with APC-Cy7.

Mpg/ Rat Mpg ELISA Kit
ELI-49759r 96 Tests
EUR 886

3-Methyladenine
2249-100
EUR 251

3-Methyladenine
2249-25
EUR 109

3-Methyladenine
20-abx076685
  • EUR 481.00
  • EUR 258.00
  • 100 mg
  • 20 mg
  • Shipped within 5-12 working days.

3-Methyladenine
A8353-200 200 mg
EUR 189
Description: 3-Methyladenine is an inhibitor of class III phosphoinositide 3-kinase (PI3K) [1].3-Methyladenine is widely used as an autophagy inhibitor through inhibiting class III PI3K without significantly affecting protein synthesis or ATP levels.

3-Methyladenine
A8353-5.1 10 mM (in 1mL DMSO)
EUR 108
Description: 3-Methyladenine is an inhibitor of class III phosphoinositide 3-kinase (PI3K) [1].3-Methyladenine is widely used as an autophagy inhibitor through inhibiting class III PI3K without significantly affecting protein synthesis or ATP levels.

3-Methyladenine
A8353-50 50 mg
EUR 108
Description: 3-Methyladenine is an inhibitor of class III phosphoinositide 3-kinase (PI3K) [1].3-Methyladenine is widely used as an autophagy inhibitor through inhibiting class III PI3K without significantly affecting protein synthesis or ATP levels.

3-Methyladenine
A8353-500 500 mg
EUR 328
Description: 3-Methyladenine is an inhibitor of class III phosphoinositide 3-kinase (PI3K) [1].3-Methyladenine is widely used as an autophagy inhibitor through inhibiting class III PI3K without significantly affecting protein synthesis or ATP levels.

3-Methyladenine
HY-19312 500mg
EUR 422

Rat Thymine DNA Glycosylase (TDG) ELISA Kit
QY-E11861 96T
EUR 374

Uracil DNA Glycosylase
7-03778 2,000U Ask for price

Uracil DNA Glycosylase
7-03779 10,000U Ask for price

Uracil DNA Glycosylase
7-03780 20,000U Ask for price

Uracil DNA Glycosylase
M1234-1000
EUR 213

Human Uracil DNA Glycosylase ELISA kit
E01U0076-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Uracil DNA Glycosylase ELISA kit
E01U0076-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Uracil DNA Glycosylase ELISA kit
E01U0076-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Uracil DNA Glycosylase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Furthermore, each rrs gene and different phylogenetic analyses confirmed that distinctive clades of the Lachnospiraceae, Bacteroidales, and Gammaproteobacteria are predominant within the Tammar foregut microbiome. Nucleotide composition-based sequence binning facilitated the assemblage of greater than two megabase pairs of genomic sequence for one of the novel Lachnospiraceae clades (WG-2). These analyses present that WG-2 possesses quite a few glycoside hydrolases focusing on noncellulosic polysaccharides.

 

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